India: TB drug resistance weaker than feared, survey suggests
WHO projections put incidence at 12 per cent, survey hints at 9 per cent
Initial indications from the the first-ever tuberculosis drug resistance survey commissioned by the Ministry of Health show that around 2 per cent of new TB cases are resistant to some TB drugs while about 9 per cent of patients who have undergone TB treatment previously and have again been diagnosed with the disease are infected by the drug-resistant variety.
The interim results of the survey are still awaited but ministry
sources say the findings are encouraging because WHO projections
had put incidence of resistance in the 12 per cent range.
The
trends were discussed in a meeting in the ministry Tuesday on
Revised National Tuberculosis Control Programme. Of the 4,840 TB
cases enrolled in the survey so far, 3,061 are new while 1,779
were previously treated. Among new patients, 70-odd had been
started on treatment for drug-resistant TB; among previous
patients the figure was about 160. Patients who were treated
previously but were diagnosed with TB again are important
because they are more likely to spread the disease and chances
of drug resistance are more in old patients. The survey aims to
clock 5,214 enrolments.
“No survey had ever been done in India to actually find
out the extent of drug resistance among TB patients. That is why
this survey was commissioned in September 2014. The interim
results will be available sometime next year as enrolments are
yet to be completed but initial trends show there is an
incidence of 2.3 per cent drug resistance in new TB patients and
about 8-9 per cent in those who had been previously treated.
This is far less than the WHO projections,” said a source
who was present in the meeting.
Between 2007 and
2015, the number of presumptive cases tested for
multi-drug-resistant TB was 6,51,640 of whom 82,452 were
diagnosed with TB of the MDR variety. “These were WHO
figures and not data from actual surveys. They were extrapolated
data from surveys and though we never believed this 12 per cent
figure the survey was commissioned under the impression that
maybe the resistance incidence would be to the tune of 10 per
cent. Initial indications that it may not touch 10 per cent even
in previously treated cases are very encouraging,” said an
official in the ministry.
The ministry, meanwhile,
has also lined up new initiatives including a missed-call
campaign to reach out to TB patients. Since the disease was made
notifiable in 2012, 2,78,171 cases have been notified, many of
them from the private sector.
Source:
The Indian Express