Could a 100-year-old TB vaccine help scientists find a better one?

Development of more effective TB drugs and vaccines is a pressing, unmet medical need.

A study is set to find out whether Bacillus Calmette-Guérin (BCG) vaccine — made of comparatively harmless microbial cousins to human TB — might safely work as a stand-in for real TB germs in future clinical trials to assess new drugs and better vaccines to stop the disease.