Immunological Reviews: Special issue on tuberculosis

The issue consists of 25 articles from the world's leading experts on tuberculosis. The articles inform about the basic biology of the Mycobacterium organism, factors that regulate its virulence, how the host responds to the pathogenic challenge, and collectively how this new knowledge gives promise for potential novel interventions. Given the increasing prevalence of multidrug-resistance tuberculosis, the control of disease will be possible only through a thorough understanding of this organism and its relationship to the host immune response.