An unexpected shortage of the tuberculosis drug isoniazid (Nydrazid) has hampered TB control and treatment across the U.S., the CDC reported.

With just 9,951 new cases of tuberculosis last year, the 2012 incidence reached an all-time low of 3.2 cases per 100,000 people, the CDC reported.

Globally, children bear a high burden of mortality and morbidity from tuberculosis and U.S. youngsters – despite low TB prevalence here – are not immune.

Delamanid, an investigational drug to combat tuberculosis, improves outcomes and reduces mortality among patients with the multidrug resistant form of the disease.

A paper-based device about the size of a postage stamp could improve testing for drug-induced liver toxicity in the developing world, researchers reported.

The integrase inhibitor raltegravir (Isentress) may be a good substitute for efavirenz (Sustiva) in HIV patients starting treatment for HIV and tuberculosis (TB) at the same time, a researcher said here.