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News

Brief news reports on Tuberculosis

TAG's 2023 Pipeline Report: TB Diagnostics

Treatment Action Group launches the 2023 Tuberculosis Diagnostics Pipeline Report.

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Technical brief: Access to TB testing and treatments: GeneXpert and delamanid

Médecins Sans Frontières issues a report offering case studies of two critical TB tools, GeneXpert and delamanid, and outlining actions that the corporations making them need to take to unlock access to these tools.

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Survey: Core outcome set for Phase 3 studies of pulmonary TB treatment

An international survey seeks to determine the most important outcomes to measure in Phase 3 trials of pulmonary TB treatment.

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TB REACH Wave 11 now open for proposals

The TB REACH Wave 11 call for proposals is focused on innovative approaches to integrate TB service delivery with lung health at the primary and community level of the health systems.

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New guidance documents to support implementation of next generation sequencing to detect DR-TB

The World Health Organization issues two new guidance documents to support implementation of next generation sequencing to detect drug-resistant TB.

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Cancer therapy shows promise against TB

A promising new cancer therapy also appears extremely potent against one of the world’s most devastating infectious diseases: tuberculosis (TB).

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Potential therapeutic target found to combat TB, a disrupted NAD(H) homeostasis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism — the intrinsic link between metabolism in immune cells and their immune function. The pathogen M. tuberculosis is known to disrupt a metabolic pathway called glycolysis in infected myeloid cells, which include macrophages, through an unclear mechanism. 

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Global meeting on strengthening public-private provider engagement outlines key actions to accelerate the TB response towards reaching commitments made by world leaders at the 2023 UN HLM on TB

Over 130 participants from countries, partners and civil society came together at the Global Meeting of the Working Group on Public-Private Mix for TB prevention and care (PPM Working Group). The meeting, held on 12 November in Paris, France, was convened by the World Health Organization (WHO) and Stop TB Partnership with support from the US Agency for International Development (USAID) and the Global Fund. The meeting was organized on the sidelines of the 53rd Union World Conference on Lung Health.

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The key to overcoming the dual burden of TB and HIV

For people living with HIV, tuberculosis is a big problem. It is the leading cause of death among those with HIV, who are 14 to 18 times more likely to fall ill with the disease than those without HIV, according to the World Health Organization. Latent TB infections can more easily progress to full disease due to the weakened immune system of people with HIV. Around 1 in 3 AIDS-related deaths in 2021 were also due to TB.

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WHO launches new e-course on the management of TB in children and adolescents

On World Children’s Day, that commemorates the adoption of the Convention on the Rights of the Child, WHO is announcing the launch of a new e-course on the management of tuberculosis in children and adolescents. The course will contribute towards ensuring universal access to TB prevention and care for children and adolescents.

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