CYP2B6 genotype was a stronger predictor of efavirenz concentrations than rifampicin-based anti-TB therapy in South African children, according to results of a three-way comparison. The researchers believe their findings do not support higher efavirenz doses in children taking rifampicin.

A protein at the center of Parkinson’s disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis, according to a UC San Francisco-led research team.

04 September 2013 - Geneva - The Stop TB Partnership will host a meeting on 31 October 2013 for all partners and other people who are visiting Paris for the World Conference on Lung Health.

LOUISVILLE, Colo., September 4, 2013 – GlobeImmune, Inc., announced today that it has been awarded a $4 million Research Project Grant (R01) by the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) to support the development of Tarmogen^® immunotherapy products to treat and prevent tuberculosis infection.

South African mine workers have always lived in mortal fear of tuberculosis. They saw miners disappearing into grim hospitals and never returning. It was seen as the end of life.

IMX313, Imaxio’s antigen re-engineering technology, has been administrated for the first time in humans as part of a tuberculosis vaccine phase I clinical trial managed by the Jenner Institute at Oxford University.

Abstract

Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) – can we continue to tackle these separately? According to the Global TB Report (2012), in 2011, out of 8.7 million people who developed TB worldwide 1.1 million (13%) were HIV positive. An approximate of 0.4 million HIV-associated TB deaths took place in 2011 and TB is the most common opportunistic infection among people living with HIV (PLWH).  HIV increases chances that latent TB infection can become active TB disease and also increases the risk of death due to this.

Korea recorded 40,000 new cases of tuberculosis (TB) infections last year, a government report showed Sunday, hinting the country still needs more attention on the disease usually found in developing countries.

Perhaps no other disease has had such a dramatic influence on art, music and literature. Now science has shown that tuberculosis is as old as humanity itself.