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Brief news reports on Tuberculosis

AusAID commits support to TB Alliance to advance new TB drugs

New York, USA: The Global Alliance for TB Drug Development (TB Alliance) has received a grant from the Australian Agency for International Development (AusAID) to support the advancement of the largest pipeline of potential new TB drugs. This one-year $2.5 million grant funds further development of urgently needed new TB treatments to combat the global epidemic, which is growing increasingly resistant to today’s available therapies. TB Alliance received this support as part of Australia’s first set of grants to fund new product development to treat diseases of poverty.

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WHO: Health research is essential for progress towards universal health coverage

At the launch of the "World health report 2013: Research for universal health coverage", WHO today called on countries to continue investing in local research in order to develop a system of universal health coverage tailored to each individual country’s situation. With universal health coverage, countries can help ensure that citizens obtain the health services they need without suffering financial hardship when paying for them.

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Anti-tuberculosis drug resistance among new and previously treated sputum smear-positive TB patients in Uganda: Results of the first national survey

Abstract

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TB testing strategies lack positive predictive value in HIV+ of India

Various testing approaches including chest x-ray and cough for at least 2 weeks lacked positive predictive value and specificity in determining which symptomatic but ambulatory HIV patients had pulmonary tuberculosis in Chennai and Pune, India.

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Combating TB/HIV co-infection

Meena (name changed), a 35 years old mother of 3, comes from a village in district Gonda of Uttar Pradesh, India. She is living with HIV and has suffered from TB also. I met her at the antiretroviral therapy (ART) centre of a Government Hospital in Lucknow and was instantly struck by her infectious smile and cheerful disposition. Three years ago, both she and her husband were diagnosed with HIV. She was immediately put on ART, but not her husband as the doctor did not find his CD4 count below the critical level. Ironically, her husband died six months later of a fall, but Meena is still up and about.  She has completed a two years anti-TB treatment regimen which was started alongside ART. Initially she bought the TB medicines from the private market spending around Rs 3500 (approximately USD 70) a month. Later on she started getting them for free from a government hospital. Every month she travels a distance of 150 km to Lucknow to collect her ART medicines. Luckily her children are all HIV negative.

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Tuberculosis vaccine could be key to combating allergies and other ailments, according to Melbourne researchers

A vaccine to prevent a lethal infectious disease could hold the key to combating Australia's allergy epidemic.

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New hope for improved TB treatments

Researchers at the University of Southampton have identified new markers of tuberculosis (TB) that may help in the development of new diagnostic tests and treatments.

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Study: PEPFAR focus countries saw significant impact on TB sickness and deaths

With tuberculosis both the most common opportunistic illness and leading cause of death for people living with HIV, the connection between the two diseases has been documented and observed. What has been less documented is the impact of increased HIV responses on tuberculosis rates in countries hard hit by both epidemics.

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Stop TB Partnership joins partners celebrating the 2013 International Day of the World's Indigenous People

09 August - Geneva - The Stop TB Partnership's mission is to serve every person who is vulnerable to tuberculosis (TB) and ensure that high-quality diagnosis, treatment and care is available to all who need it. Indigenous peoples are often poor and marginalized and it is among such groups that the burden of TB is highest. A large share of the 370 million indigenous peoples living in 70 countries, have a high burden of health challenges and low access to diagnosis, treatment and care. In industrialized countries, TB incidence and mortality rates are generally several times higher among indigenous peoples than among others born in those countries. Fighting TB among indigenous peoples is therefore at the heart of the Stop TB Partnership’s mission.

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Key to tuberculosis cure lies in the starving of the enemy

Scientists at the University of Surrey have undertaken research into tuberculosis which could result in quicker treatment for sufferers and potentially reduce the problem of drug-resistance.  The study was recently published in the journal Cell Chemistry and Biology  

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