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Items tagged with Diagnostics

New laptop program can identify drug resistance from bacterial genomes (post)

Scientists have developed an easy-to-use computer program that can quickly analyse bacterial DNA from a patient's infection and predict which antibiotics will work, and which will fail due to drug resistance. The software is currently being trialled in three UK hospitals to see whether it could help speed up diagnosis of drug-resistant infections and enable doctors to better target the prescription of antibiotics.

Device focuses on speedier tuberculosis diagnosis (post)

-- Device automatically photographs samples and identifies bacteria
-- It could halve diagnosis time and lower infection risk for technicians
-- But it will still require high-security labs and skilled technicians

Most commonly used TB test fails to accurately diagnose pregnant HIV-positive women (post)

New research finds that the most commonly used test for tuberculosis fails to accurately diagnose TB in up to 50 percent of pregnant women who are HIV-positive. The research published early online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine is believed to be the first study to compare the accuracy of two TB tests -- the Quantiferon Gold In Tube® blood test and the more commonly used TST or tuberculin skin test -- in this population.

Xpert MTB/RIF for tuberculosis testing: access and price in highly privatised health markets (post)

Xpert MTB/RIF (Cepheid, Sunnyvale, CA, USA) is the biggest recent advance in tuberculosis diagnosis, and since 2010 more than 15 million cartridges have been procured through concessional pricing ($9·98 per cartridge in 2015).1 However, even in countries with a high tuberculosis burden, the private sector is not eligible for concessional pricing for Xpert, nor for other WHO-endorsed tests such as line probe assays (LPA) and liquid cultures. Manufacturers set higher prices for reagents and instruments for private laboratories and institutions than for the public sector, and there are additional costs (such as import duties), and margins imposed by distributors, intermediaries, and laboratories.

Resources for TB diagnostic product developers (post)

Prof Madhukar Pai, MD, PhD, of McGill University compiled links to several helpful resources, including TB diagnostics landscape and market analyses, target product profiles for priority TB diagnostics, and a list of frequently asked questions to facilitate the development of new TB diagnostic tools.

FIND signs partnership agreement with McGill on TB diagnostics (post)

FIND is pleased to announce the finalization of a memorandum of understanding with the Research Institute of the McGill University Health Centre in Montreal, with a focus on tuberculosis (TB) diagnostics.

Abbott to acquire Alere, becoming leader in point of care testing and significantly advancing global diagnostics presence (post)

Abbott gains leadership in the $5.5 billion point of care segment, broadens diagnostics footprint and enhances access to fast-growing diagnostics channels

- Transaction expected to be immediately accretive to Abbott's ongoing earnings per share upon close
- Acquisition will provide access to new product applications, channels and geographies
- Alere's complementary technologies will help Abbott provide better care for patients by meeting the growing demand for fast, accurate and actionable medical information

India: Drug-resistant TB detection within 2 hours (post)

For the task, the ministry has procured 500 GeneXpert machines that will provide results of drug-resistant TB within two hours against the conventional diagnostic tools which take up to two months.

TB PCR test effective for intrathoracic granulomatous lymphadenopathy diagnosis (post)

The use of the polymerase chain reaction for Mycobacterium tuberculosis test using endobronchial ultrasound-guided transbronchial needle aspiration was effective in diagnosing intrathoracic granulomatous lymphadenopathy, even among some patients with non-diagnostic results, according to recent research.

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