Items tagged with Diagnostics
Urine colorimetry to detect low rifampin exposure during tuberculosis therapy: a proof-of-concept study (post)
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Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis (post)
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Faster detection of pathogens in the lungs (post)
What used to take several weeks is now possible in two days: Thanks to new molecular-based methods, mycobacterial pathogens that cause pulmonary infections or tuberculosis can now be detected much more quickly. Time-consuming bacteria cultures no longer need to be taken from the patient samples, meaning that a suitable therapy can be started quickly.
Rapid TB test accuracy in West Africa compromised by mycobacterium diversity (post)
World-wide, Mycobacterium tuberculosis (Mtb) is responsible for the vast majority of tuberculosis (TB) cases. However, there are several other closely related mycobacterial species that cause TB, all part of the Mycobacterium tuberculosis complex (Mtbc). One of them, Mycobacterium africanum (Maf), causes up to 40% of TB cases in West Africa. TB diagnosis across Africa relies largely on tests optimized to detect Mtb. A study led by the Medical Research Council Unit The Gambia and the Antwerp Institute of Tropical Medicine, Belgium, published in PLOS Neglected Tropical Diseases now suggests that in West Africa tests to identify Mtbc in culture miss a substantial fraction of cases, with dire consequences for the patients and for TB control efforts.
Connectivity of diagnostic technologies: improving surveillance and accelerating tuberculosis elimination (post)
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Evaluation of the GenoType MTBDRplus assay for detection of rifampicin- and isoniazid-resistant M. tuberculosis isolates in central Ethiopia (post)
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Screening strategies for active TB: focus on cost-effectiveness (post)
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