Items tagged with Diagnostics
Are oral swabs the future of TB testing? (post)
The World Health Organization (WHO) estimates that every year 40% of people who fall ill with tuberculosis (TB) globally are not diagnosed. There is thus an urgent need for faster, safe, and more convenient TB tests. The current gold standard of testing still requires people to cough up sputum, something that some people and children, in particular, struggle with. The coughing up of sputum also poses an infection risk to healthcare workers collecting sputum samples.
New blood test can help doctors diagnose TB and monitor treatment (post)
Researchers at Tulane University School of Medicine have developed a new highly sensitive blood test for tuberculosis (TB) that screens for DNA fragments of the Mycobacterium tuberculosis bacteria that causes the deadly disease.
Bringing TB screening services to communities in Nigeria through new tools (post)
To increase screening in hard-to-reach areas, and to help close the TB diagnostic gap in Nigeria, the Stop TB Partnership's Introducing New Tools Project (iNTP) and partners USAID and the Nigeria National TB Program, has been supporting KNCV Nigeria and the Institute of Human Virology, Nigeria (IHVN) in rolling out ultra-portable X-Ray and computer-aided detection technology throughout the country. Watch the video to see the use of this game changing technology in action!
Training modules on ultra-portable X-ray, computer-aided detection of TB and Truenat testing launched (post)
The Stop TB Partnership, in collaboration with USAID and its Infectious Disease Detection and Surveillance project (IDDS), have developed packages of customizable training modules for countries to adapt, using the Introducing New Tools Project (iNTP).
WHO call for expressions of interest: Generation of data to externally validate treatment decision algorithms for TB in children (post)
The World Health Organization's Global TB Program and the Special Program for Research and Training in Tropical Diseases are seeking expressions of interest from independent researchers/research groups, academic institutions or other entities with relevant expertise and experience in conducting research on paediatric TB diagnostic approaches.
South Africa: Positive signs for new TB testing strategy (post)
Under a new TB diagnosis strategy, people considered to be at high risk of TB are offered molecular TB tests, even if they do not have any symptoms. A landmark study in 2020 showed that such a strategy can help diagnose more people more quickly. Now, early indications are that it also works in the real world and South Africa’s lab service says they can cope with the increased demand.
South Africa: New TB testing strategy brings hope, but work remains (post)
A new tuberculosis (TB) testing strategy has been available in South Africa since April this year, hoping to diagnose more people. Labelled a potential game-changer, an expert warns that issues like stigma and treatment barriers mustn’t be left behind.
Dartmouth’s Geisel School of Medicine team finds increased rate of TB infection among adolescents in Tanzania (post)
Published today in PLOS ONE, “Serial T-SPOT.TB responses in Tanzanian adolescents: transient, persistent and irregular conversions”, investigators from the Geisel School of Medicine and Muhimibili University of Health and Allied Sciences (MUHAS) report high rates of new tuberculosis (TB) infection among adolescents in Tanzania. Multiple blood tests for TB infection were conducted over three years in 650 schoolchildren age 13-15 and showed that the risk of acquiring new TB infection was 3 percent per year. In addition, by performing six or more blood tests on each volunteer with an interferon gamma release assay (IGRAs) the study team identified new patterns of transition between positive and negative IGRA tests for TB infection.
Webinars on artificial intelligence-based imaging in TB (post)
To facilitate south-south learning on early experiences and exchange lessons learned on computer-aided detection (CAD) and X-ray implementation and to meet global demand for support in rolling these digital tools, the Stop TB Partnership launched a global platform that brings together prospective, early, and experienced implementers debuting with two webinars in June.
Nanopore sequencing may improve the accuracy of pulmonary TB diagnoses (post)
The use of nanopore sequencing for the early identification of pulmonary tuberculosis (TB) infection had superior diagnostic accuracy compared with both Mycobacterium tuberculosis (MTB) culture analyses and Xpert MTB/rifampin (RIF) assays, according to results of a study published in International Journal of Infectious Diseases.
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