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Items tagged with Drug-resistant TB

EU and Russia collaborate in new project on infectious diseases (post)

A new EU project on the theme of HIV, hepatitis C and tuberculosis is a door opener for collaboration between researchers from EU countries and Russia. One of the project’s initiators is Anders Sönnerborg, Professor of Clinical Virology and Infectious Diseases at KI’s Departments of Laboratory Medicine, and Medicine Huddinge. The project Common Actions Against HIV/TBC/HCV Across the Regions of Europe (CARE) will mainly focus on the spread of the infections and resistance to treatment.

Vitamin D helps treat lethal drug-resistant TB (post)

Vitamin D has been found to speed up the clearance of tuberculosis (TB) bacteria from the lungs of people with multi-drug resistant TB, according to a study of 1,850 patients receiving antibiotic treatment, led by Queen Mary University of London.

Drug-resistant TB: high mortality rate due to inaccurate tests (post)

Inaccurate tests carried out on tuberculosis patients in developing countries often fail to reliably detect resistance to drugs, leading to incorrect treatment and a higher mortality rate. These are the results of study by an international group of researchers led by a team at the University of Bern published today (January 8).

Multidrug-resistant TB outcomes with pyrazinamide susceptibility testing (post)

Introducing pyrazinamide molecular susceptibility testing in the treatment of multidrug-resistant tuberculosis improved outcomes without the use of new drugs and shortened the World Health Organization (WHO) 20+ month regimen to 12 months, according to a study published in the European Respiratory Journal.

India: Delamanid to be available across the country (post)

Crucial anti-Tuberculosis (TB) drug Delamanid will now be available across India. Until currently, its supply was restricted to seven States.

Physicists develop a new method to identify antibiotic-resistant bacteria (post)

A team of physicists from Immanuel Kant Baltic State University have suggested a method to identify single antibiotic-resistant tuberculosis-causing bacteria. The new method detects the bacteria and evaluates their resistance to antibiotics without damaging the biological sample. The results of the first trial of the method were published in Data in Brief.

As patients challenge patent, J&J commits to tackling drug-resistant TB (post)

Johnson & Johnson has tripled its commitment on tuberculosis drug Bedaquiline by offering 90,000 doseages to its global donation programme that ends in March, Paul Stoffels, J&J’s Vice-Chair of the Executive Committee and Chief Scientific Officer, said, on a programme that has given medicines to India as well.

India’s drug-resistant TB patients face delayed and confusing diagnoses, treatment (post)

Mumbai: Drug-resistant tuberculosis (DR-TB) patients in India face delayed diagnoses, different treatment pathways from both public and private health care systems and differing costs for the same treatments from different providers in an unregulated private health care sector, says a January 2019 study published in Public Library of Science (PLOS), a scientific journal.

CROI 2019: Study demonstrates cardiac safety of bedaquiline plus delamanid for MDR-TB (post)

SEATTLE — Phase 2 study data presented at CROI demonstrated the cardiac safety of the combined use of bedaquiline and delamanid — two novel tuberculosis medications — in patients with multidrug-resistant TB receiving multidrug background treatment.

TB medicine pretomanid enters regulatory review process in the United States (post)

NEW YORK, NY (March 8, 2019)—TB Alliance’s new drug application (NDA) for the novel tuberculosis (TB) drug candidate pretomanid has been accepted for review by the United States Food and Drug Administration (FDA). The application is for the use of pretomanid as part of a new regimen, in combination with bedaquiline and linezolid, for the treatment of extensively drug-resistant (XDR) TB, treatment intolerant multidrug-resistant (MDR) TB, and treatment non-responsive MDR-TB.

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