Items tagged with HIV coinfection
Post-TB lung disease in HIV-associated TB common (post)
Post-tuberculosis (TB) lung disease is common in patients with human immunodeficiency virus (HIV)-associated TB at high risk for TB-associated immune reconstitution inflammatory syndrome (TB-IRIS), according to study results published in the European Respiratory Journal.
Webinar: Latest updates on TB and DR-TB in people living with HIV (post)
The International AIDS Society (IAS) will host a webinar under the theme 'Latest updates on TB and drug-resistant TB (DR-TB) in people living with HIV' on 18 February 2020.
Alarmingly high mortality in hospitalised patients with HIV/TB co-infection in Malawi and South Africa (post)
A study from South Africa and Malawi published online ahead of print in Clinical Infectious Diseases highlights the urgent need for better management of people with TB and HIV co-infection. It shows how suboptimal implementation of TB and HIV standards of care is causing unnecessary human suffering and untimely deaths in people living with co-infection. This study reinforces the necessity of due diligence in ensuring that every component of the evidence-based model of care for TB and HIV is taken care of.
High death rate for HIV-associated meningitis reported in African hospitals (post)
Evidence review finds approximately half of hospital patients with cryptococcal, tuberculosis or pneumococcal meningitis died within two weeks or during hospitalisation.
CROI 2020 TB round up (post)
Treatment Action Group (TAG) released an overview of TB data reported at the 2020 Conference on Retroviruses and Opportunistic Infections (CROI) virtually held on 8-11 March 2020. A summary of major findings, TAG’s take on them, and high-level summaries of select findings are available here.
MSF technical briefs (post)
Médecins Sans Frontières (MSF) updated two of its technical briefs, A rapid TB test for people living with HIV and Making the switch.
UNAIDS: Tuberculosis — good progress, but not enough (post)
As the world is commemorating World TB Day on 24 March in the midst of the COVID-19 pandemic, it is critical to remember that we need to sustain services for addressing TB epidemics and TB/HIV coinfections globally. There is still a US$ 3.3 billion yearly funding shortfall for TB prevention and care.
Pulmonary TB enhances HIV-1 antibody responses (post)
Active infection with Mycobacterium tuberculosis (TB) enhances anti-HIV-1 antibody response, which may then lead to the emergence of broadly neutralizing antibodies (bnAbs) that target conserved envelope domains.
Darunavir/ritonavir with rifampicin may be hepatotoxic (post)
Darunavir/ritonavir administered with rifampicin causes hepatotoxicities in people living with HIV, according to results of a study published in the Journal of Antimicrobial Chemotherapy.
TB alone and with HIV co-infection: Treatment updates (post)
In patients with a history of tuberculosis (TB), the odds of residual pulmonary impairments are 2- to 3-fold higher compared with individuals with no TB history, with especially high rates in patients with multidrug-resistant TB.1 HIV has been identified as an independent risk factor for predominantly obstructive impairment in lung function. However, there is a dearth of research regarding lung function in HIV-associated TB because patients with HIV are frequently excluded from relevant studies, despite the fact that an estimated 40% of deaths in people with HIV have been attributed to TB.1,2
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