Items tagged with Pediatrics
Study shows scaling up TB prevention in children is possible (post)
THE HAGUE, Netherlands, October 25, 2018 – Children – especially very young children – are at high risk of developing severe tuberculosis illness when exposed to a member of their household who has active disease, but only 23 percent of child contacts of adults with active disease are provided with TB preventive therapy, researchers said here. That leaves 1.3 million children under the age of five who are eligible for isoniazid preventive therapy without access to the intervention that would prevent illness, according to the World Health Organization. Preliminary results from a study released here show how that can change.
Childhood TB and stigma (post)
A book telling the powerful stories of 13 child tuberculosis (TB) survivors and their families was launched today (October 24) at the 49th Union World Conference, to raise awareness of childhood TB and stigma.
TB Alliance receives GHTC Partnership Award for development of child-friendly TB medicines (post)
[November 28, 2018, WASHINGTON, D.C.] – TB Alliance and partners were honored today as the winner of the Global Health Technologies Coalition (GHTC) 2018 Innovating for Impact Partnership Award, for the development of improved child-friendly tuberculosis (TB) medicines. Since the improved medicines were introduced in 2016, 85 countries have procured more than 800,000 treatment courses. Appropriately-dosed and palatable, these new medicines are improving TB treatment and survival for the estimated one million children stricken with TB each year.
BCG vaccine scars tied to decline in infant mortality (post)
Scarring caused by bacillus Calmette-Guérin, or BCG, vaccine in both mothers and infants was associated with a significant decrease in infant mortality, according to findings from a randomized controlled trial published in the Journal of the Pediatric Infectious Diseases Society. The researchers wrote that the effect of the tuberculosis vaccine on mortality was not as strong when only the child had scarring.
Webinar on outcomes of PADO-TB 1 (post)
The Global Accelerator for Paediatric Formulations (GAP-f) will host a webinar on 27 February 2019 to report on the outcomes of the Paediatric Antituberculosis Drug Optimization 1 Meeting (PADO-TB 1) that took place on 13-14 February 2019.
Weight-age score predicts effectiveness of childhood TB therapy (post)
Weight change early in therapy predicted outcomes of childhood tuberculosis therapy, according to study results published in the Journal of the Pediatric Infectious Diseases Society.
QuantiFERON-TB Gold-Plus performance in children with confirmed TB (post)
Although the new interferon-gamma release assay QuantiFERON-TB Gold Plus® (QFT-Plus) had good sensitivity in children with pulmonary tuberculosis (TB) only, QFT-Plus had poor sensitivity in children with extra-pulmonary TB only, according to a study published in PLoS One.
Levofloxacin pharmacokinetics in children with drug-resistant TB exposure (post)
According to data published in Antimicrobial Agents and Chemotherapy, the dosing recommendations regarding levofloxacin for the treatment and prevention of drug-resistant tuberculosis (DR-TB) in children may need to be re-evaluated.
International $6 million grant to study HIV/TB coinfection in kids (post)
PITTSBURGH, 1/5/2019 – About a third of us are walking around with the bacteria that causes tuberculosis (TB) in our bodies, but most don’t actually end up with TB. For children living with HIV – about 2 million at last estimate – it’s a different story. They’re much more likely to develop TB, and about 40,000 HIV-positive children die from it each year.
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