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Items tagged with Pediatrics

Testing multiple noninvasive specimen types may improve diagnosis of pediatric TB (post)

The far less-invasive collection and testing of nasopharyngeal aspirate (NPA) samples in combination with stool and urine sample testing may improve the diagnosis of tuberculosis (TB) in children in limited-resource settings. This finding from a prospective, cross-sectional diagnostic study, was published in JAMA Pediatrics.

Ending HIV in children is way off target: where to focus action now (post)

World leaders have recently, under the auspices of the United Nations, renewed their commitment to ending AIDS. The new phase offers much needed hope for the future, provided the commitments made are fulfilled.

Child and adolescent TB training for healthcare workers (post)

Tuberculosis causes disease in more than 1.5 million children and adolescents (<20 years) globally each year. It is a leading cause of mortality in these age groups in tuberculosis-endemic countries, and adolescents with tuberculosis are also a common source of transmission.

CHMP grants positive opinion for Otsuka’s child-friendly 25 mg dispersible tablet formulation of Deltyba (post)

CHMP grants positive opinion in the European Union for Otsuka’s child-friendly 25 mg dispersible tablet formulation of Deltyba® (delamanid) for the paediatric population weighing at least 10 kg with pulmonary multidrug-resistant TB

Indonesia, Nigeria: Children at increased risk of TB (post)

The Ministry of Health of Indonesia released TB Care School Guidelines to support the efforts to prevent the TB transmission in schools. For more information, click here.

WHO issues rapid communication on updated guidance for the management of TB in children and adolescents (post)

26 August 2021 | Geneva - A rapid communication released by the World Health Organization (WHO) Global Tuberculosis Programme has announced important updates to guidance on the management of tuberculosis (TB) in children and adolescents. This includes new recommendations on diagnostic options, treatment regimens, as well as treatment decision algorithms and optimal models of care for the delivery of child and adolescent TB services.

Vitamin D deficiency does not increase TB risk in young children (post)

Low Vitamin D levels have been hypothesised by some experts to be a risk factor for tuberculosis (TB). People who develop TB often present with low Vitamin D levels when they are diagnosed. However, whether Vitamin D levels at one point predispose a child to developing TB is debated and not clear.

Vietnam leads the way with SOS Stool Method to diagnose TB (post)

Vietnam is the first country in the world to routinely use an innovative method to diagnose tuberculosis (TB) using stool. The Simple One-Step Stool Method, developed by KNCV Tuberculosis Foundation, is implemented in 10 healthcare facilities across the country. ,,This simple and painless test is an important development for diagnosing TB in children under the age of five and people living with HIV. This can save many lives and reduce suffering”, says Prof. Dr. Nguyen Viet Nhung, Director of the National Lung Hospital and Head of the Vietnam National Tuberculosis Control Program (NTP).  

Five developments in paediatric TB (post)

The screening, diagnosis, and treatment of tuberculosis (TB) in children remain far from optimal – and in many respects lag behind what can be done for adults.

Optimal dosing of rifampicin/isoniazid/pyrazinamide in children with TB (post)

Treatment with an updated fixed-dose combination (FDC) of rifampicin/isoniazid/ pyrazinamide may decrease the risk for insufficient exposure to rifampicin among children with tuberculosis (TB) infection, according to results of a prospective study published in Clinical Infectious Diseases.

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