Items tagged with Pediatrics
Why is the 100-year-old BCG vaccine so broadly protective in newborns? (post)
The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world’s oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There’s even some evidence that it can reduce severity of COVID-19.
20% of multidrug-resistant TB cases in children could be averted by household testing and treatment (post)
New modelling study suggests that testing household contacts and preventive treatment could avert almost 4,000 deaths in children under 15 globally every year.
WHO call for expressions of interest: Generation of data to externally validate treatment decision algorithms for TB in children (post)
The World Health Organization's Global TB Program and the Special Program for Research and Training in Tropical Diseases are seeking expressions of interest from independent researchers/research groups, academic institutions or other entities with relevant expertise and experience in conducting research on paediatric TB diagnostic approaches.
Global TB Caucus: TB video series (post)
The Global TB Caucus released a three-part video series: shorter-form primers that can easily inform people on key topics in the discussion surrounding TB.
ICMR to begin study to evaluate BCG booster dose for kids, adolescents (post)
This study will demonstrate the effect of BCG revaccination in comparison to oral chemoprophylaxis on the incidence of mycobacterium tuberculosis disease in healthy household contacts, aged 6-18 years.
Experts weigh in on the potential of ultrasound for diagnosing TB in kids (post)
Tuberculosis (TB) is hard to diagnose in children, especially very young ones. This is because it is difficult for children to cough up the sputum required to perform the gold standard molecular TB test. Even if they do manage to cough up sputum, there may not be enough TB bacteria in it for a positive diagnosis since children’s sputum harbours fewer bugs than that of adults.
Dolutegravir twice-daily dosing in children with HIV-associated TB: a pharmacokinetic and safety study within the open-label, multicentre, randomised, non-inferiority ODYSSEY trial (post)
Children with HIV-associated TB have few antiretroviral therapy options. A study, published in The Lancet HIV, evaluated the safety and pharmacokinetics of dolutegravir twice-daily dosing in children receiving rifampicin for HIV-associated TB.
TB vaccine passes safety test (post)
The vaccine candidate VPM1002 shows its safety in a study with HIV- and non-HIV-exposed newborns.
Immune boosting benefits of TB vaccine seen in infants more than a year after vaccination (post)
The immune boosting benefits of a tuberculosis vaccine can be seen in infants more than one year after vaccination, according to a new study.
BCG vaccine prevents TB in young children, but not adults (post)
Amidst longstanding debate on the effectiveness of the tuberculosis vaccine, a new study suggests that the vaccine is protective against TB in children under 5, but adolescents and adults in high-burden countries may need additional protection to maintain immunity beyond childhood.
Page 21 of 31 · Total posts: 0
←First 20 21 22 Last→