Items tagged with Pediatrics

Children with TB at risk of dying amid slow progress on child-friendly treatment (post)

More than half a million children who fall ill with tuberculosis each year are at risk of dying because of a lack of child-friendly treatments, experts said.

Child TB Learning Portal launches with free online course (post)

The Union, in collaboration with the World Health Organization, has launched a free interactive online course, Childhood TB for Healthcare Workers. The six-module course is the first offering of the new Childhood TB Learning Portal funded through TB CARE I.

One in eight TB cases in children is isoniazid-resistant (post)

Isoniazid-resistant tuberculosis (TB) is more common than had been thought among children, particularly in Europe, according to the results of a study published online June 1 in Pediatrics.

Poor specificity of TB skin test may lead to overtreatment in children (post)

Tuberculin skin testing resulted in poorer specificity when compared with a commercial interferon-gamma release assay in identifying latent tuberculosis among a cohort of internationally adopted children.

A new lease on life for children with TB meningitis (post)

Children with tuberculous (TB) meningitis now have a better chance of survival, thanks to a study at Stellenbosch University (SU).

Start of phase 2 trial in newborn infants in South Africa with VPM1002, a new vaccine developed by an Indo-German co-operation for prevention of tuberculosis (post)

08.07.2015 -- Enrollment of the first infant in a phase 2 clinical trial of a new vaccine to prevent tuberculosis (TB) has successfully started. VPM1002, the most advanced new TB vaccine in clinical development, will help curtail spread of life-threatening TB disease not only in endemic countries, but also in Europe. The vaccine candidate VPM1002 was recently out-licensed to Serum Institute of India Ltd. (SIIL), the world’s largest vaccine manufacturer according to number of doses sold. VPM1002 is developed by SIIL in collaboration with Vakzine Projekt Management GmbH (VPM). Mr. Adar C. Poonawalla, CEO and Executive Director of SIIL emphasizes that “TB still remains a major public health problem and only a new and more effective vaccine can help to restrict the expansion of multidrug-resistant and extremely drug-resistant TB and thus save the lives of millions of people each year. We are pleased with the start of this trial as it represents one more step in our efforts to continuously improve existing vaccines, and to make new, safe, efficacious and cost effective vaccines available to the world, especially for TB. This is also shown in our plans to start large trials with VPM1002 to address the challenges of relapsing TB in adults.”

South Africa: Children the frontline of war on TB (post)

That is the approach by provincial health and education officials who will today launch a campaign at schools to combat the disease, which is classified an epidemic by World Health Organisation standards.

Interventions to improve adherence to treatment for paediatric tuberculosis in low- and middle-income countries: a systematic review and meta-analysis (post)

Objective

To assess the design, delivery and outcomes of interventions to improve adherence to treatment for paediatric tuberculosis in low- and middle-income countries and develop a contextual framework for such interventions.

Piloting upfront Xpert MTB/RIF testing on various specimens under programmatic conditions for diagnosis of TB & DR-TB in paediatric population (post)

Abstract

Child with drug-resistant TB successfully treated at Johns Hopkins Children’s Center (post)

Johns Hopkins Children’s Center specialists report they have successfully treated and put in remission a 2-year-old, now age 5, with a highly virulent form of tuberculosis known as XDR TB, or extensively drug-resistant TB. The case, researchers say, provides the first detailed account of a young child in the United States diagnosed and treated for XDR TB.