Items tagged with Scientific research
Gates Foundation supports Technion innovation for TB (post)
Haifa (Israel) – Technion – Israel Institute of Technology announced today that it will receive Phase II funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables individuals worldwide to test bold ideas to address persistent health and development challenges. Professor Hossam Haick will continue to pursue an innovative global health research project, titled “Self-Administered Adhesive Patch for Detection of Tuberculosis”.
Don’t weaken the F.D.A.’s drug approval process (post)
During the early days of the AIDS epidemic in the 1980s, there were no effective treatments against H.I.V., the virus that causes the disease. Because of this, many thousands of people died lingering deaths. The desperation of those times led to the rise of an activist movement that took to the streets and pressed government officials to expedite research on drugs to treat AIDS.
Breakthrough for research team on TB (post)
Guwahati: A team of researchers that used samples from a genetically-homogenous tribe of Arunachal Pradesh to find the spot in the human body where the tuberculosis bacteria lies dormant, has been able to decode, localize and understand the conditions in which the bacteria lives in the Mesenchymal Stem Cells (MSC) of the bone marrow.
Tuberculosis bacteria hide in the low oxygen niches of bone marrow stem cells (post)
A new study from the Forsyth Institute is helping to shed light on latent tuberculosis and the bacteria's ability to hide in stem cells. Some bone marrow stem cells reside in low oxygen (hypoxia) zones. These specialized zones are secured as immune cells and toxic chemicals cannot reach this zone. Hypoxia- activated cell signaling pathways may also protect the stem cells from dying or ageing. A new study led by Forsyth Scientist Dr. Bikul Das has found that Mycobacterium tuberculosis (Mtb) hijack this protective hypoxic zone to hide intracellular to a special stem cell type. The study was published online on June 8th in the American Journal of Pathology.
Ethics vs economics: the cost of outsourcing clinical trials to developing countries (post)
As the death toll from the African Ebola crisis peaked, World Health Organization (WHO) Director-General Margaret Chan delivered a scathing attack on the “profit-driven” pharmaceutical industry and its unwillingness to develop a vaccine “for markets that cannot pay”.
Research reveals new insights into a key antibiotic target in the fight against TB (post)
Scientists at the University of Sussex have unraveled a key process in the bacterium that causes tuberculosis (TB), potentially paving the way for new antibiotics to fight the disease.
Towards host-directed therapies for tuberculosis (post)
The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjunct host-directed therapies.
Resistance isn’t futile – how to tackle drug-resistant superbugs (post)
Low profit margins and the difficulty of finding new drugs has led to big pharma shutting down its antibiotics programmes. But now researchers are adopting new approaches to tackle drug-resistant superbugs
MSU scientists set sights on glaucoma medication to treat TB (post)
EAST LANSING, Mich. - A new discovery by Michigan State University scientists suggests that a common medication used to treat glaucoma could also be used to treat tuberculosis, even the drug-resistant kind.
UK’s Wellcome Trust to fund Sphaera Pharma’s MDR-tuberculosis drug development (post)
Hyderabad: Sphaera Pharma Pvt. Ltd, a Gurgaon-based drug discovery and development company, on Tuesday (July 21) said UK-based biomedical research charity Wellcome Trust had agreed to fund the development of its new drug to treat multiple drug-resistant tuberculosis (MDR-TB).
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