Items tagged with Scientific research
TB: Promising new drugs for old pathogen Mtb (post)
Researchers are targeting a metabolic pathway, the dihydrofolate reductase pathway, crucial for amino acid synthesis to treat TB infections.
HIV/TB co-infection: Tunneling towards better diagnosis (post)
1.2 million people in the world are co-infected by Mycobacterium tuberculosis, the bacteria which causes tuberculosis, and HIV-1. This combination is deadly: it makes patient diagnosis and treatment difficult, and increases the pathogenicity of these two infectious agents. An international team led by researchers at the CNRS and Inserm have revealed that in the presence of tuberculosis, HIV-1 moves from one cell to the next via nanotubes which form between macrophages, drastically increasing the percentage of infected cells. These findings appear in the 26 March 2019 edition of Cell Reports.
SFU-led team fights drug-resistant TB with artificial intelligence (post)
Tuberculosis (TB) is the world’s deadliest infectious killer but a team of SFU-led researchers is determined to fight it—using artificial intelligence.
Bacteria-mimicking particles may help treat infectious diseases (post)
Unique particles modified to mimic bacteria may provide a better means of treating infectious diseases, such as tuberculosis.
New tools and strategies for TB diagnosis, care, and elimination: A PLOS Medicine special issue (post)
This week, publication of a special issue on tuberculosis (TB) begins in PLOS Medicine, advised by guest editors Richard Chaisson of Johns Hopkins University, Claudia Denkinger of the University of Heidelberg, and Mark Hatherill of the South African Tuberculosis Vaccine Institute.
Scientists discover new arsenic-based, broad-spectrum antibiotic (post)
Antibiotic resistance has been called one of the biggest public health threats of our time. There is a pressing need for new and novel antibiotics to combat the rise in antibiotic-resistant bacteria worldwide.
Detailed map of lung immune response in TB (post)
The picture on the left shows a tuberculosis (TB) infection in a mouse lung, in which immune cells form a granuloma around the bacteria. The different symbols represent working copies of active genes, called messenger RNA, which are different in the granuloma centre in comparison to the surrounding cells.
Tulane University awarded $6.1 million for postnatal HIV, TB study (post)
Tuberculosis, the world’s leading infectious disease killer, is also the leading cause of death in infants with HIV. Researchers at Tulane National Primate Research Center will use a new $6.1 million grant from the National Institutes of Health to better understand how the developing immune system responds to the two diseases so that doctors can improve outcomes for infants and children across the globe.
International $6 million grant to study HIV/TB coinfection in kids (post)
PITTSBURGH, 1/5/2019 – About a third of us are walking around with the bacteria that causes tuberculosis (TB) in our bodies, but most don’t actually end up with TB. For children living with HIV – about 2 million at last estimate – it’s a different story. They’re much more likely to develop TB, and about 40,000 HIV-positive children die from it each year.
TAGline May 2019: Nothing About Us Without Us (post)
This TAGline is all about the importance of community engagement in research to end the epidemics of HIV, HCV, and TB. As this edition’s cover shows, protestors at the “Storm the NIH” demonstration and die-in in May 1990 demanded political will and funding for research, and equitable access to treatment for HIV. This bold and knowledgeable action brought about a massive increase to investment in HIV research, and extensive changes to how AIDS clinical trials were conducted.
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