Items tagged with Scientific research

Why does TB find a 65-year-old drug so hard to resist? (post)

Since its discovery in 1954, there have been almost no recorded cases of tuberculosis becoming resistant to the antibiotic drug D-cycloserine (DCS) in patients. With resistance to many other drugs on the rise, a team of Crick researchers set out to find out why DCS has evaded resistance for so long.

Latest TB research publications (post)

NIH awards contracts to advance tuberculosis immunology research (post)

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded $30 million in first-year funding to establish new centers for immunology research to accelerate progress in tuberculosis (TB) vaccine development.

Sea sponge could be key in fight against TB (post)

An Australian sea sponge could hold the key to successfully combatting the deadly disease tuberculosis (TB), a new study from the Centenary Institute and the University of Sydney suggests.

Tuberculosis: New insights into the pathogen (post)

Researchers at the University of Würzburg and the Spanish Cancer Research Centre have gained new insights into the pathogen that causes tuberculosis. The work published in Nature provides the basis for a new approach in antibiotic therapy.

Latest TB research publications (post)

Can we reverse antibiotic resistance? (post)

In the battle against antibiotic resistance, some scientists are trying a new approach: re-sensitising bacteria to drugs they no longer respond to so that existing antibiotics can hit their target once more.

GSK candidate vaccine demonstrates sustained level of protection against active pulmonary TB (post)

-- Final analysis of phase IIb study published today in the New England Journal of Medicine and presented at the 50th Union World Conference on Lung Health.

-- Final results confirm the innovative TB candidate vaccine’s efficacy level and acceptable safety profile in three-year clinical trial conducted in sub-Saharan African regions.

From ancient tools to artificial intelligence for TB detection and intelligence (post)

23 October 2019, Geneva, Switzerland. Artificial intelligence (AI), a buzzword in the tech world, has steadily marked its presence in the field of healthcare, including in tuberculosis (TB). Recently, AI is being employed to read and screen chest x-rays for TB. These new solutions are providing hope to tackle TB, which kills more people worldwide than any single infectious disease. The Stop TB Partnership’s TB REACH is leading evaluations of multiple AI software packages to screen and triage people with TB using chest x-rays. The team published the first-ever scientific article, evaluating the accuracy of multiple AI software for detecting TB from chest x-rays now available in Nature Scientific Reports.

Anti-arthritis drug also stops TB bacillus from multiplying in blood stem cells (post)

Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells.