Items tagged with Treatment
Ambitious new U.S. plan may put hundreds of thousands on MDR-TB treatment (post)
The United States plans to place 360,000 multidrug-resistant tuberculosis patients globally on treatment over the next five years, as part of a national tuberculosis action plan currently under draft. The plan – which is due to be submitted to the White House in September – aims to promote universal MDR-TB treatment, accelerate basic TB research, and strengthen domestic capacity to combat MDR-TB, according to Administration officials who discussed the action plan with stakeholders in July.
Existential threat of drug-resistant TB (post)
In September, the Obama administration will unveil The National Action Plan to Combat Drug Resistant Tuberculosis (TB). I commend the administration for developing an action plan to address this preventable, air-borne disease. As a practicing physician who has been treating people with drug resistant TB for decades, I am cautiously optimistic that future patients will receive the safe and effective treatment regimens they need both for their own survival as well as to prevent spreading the disease in their families and communities.
TB researchers earn NIH grant to study potential for shortening treatment course (post)
Stop Jeff North, Ph.D., if you’ve heard this one before: an indole-based drug and a tuberculosis protein meet in a laboratory. There’s a brief interaction, then the drug skates merrily away while the protein is nowhere to be found.
Electronic reminders can help tuberculosis patients stay on medication (post)
Reminders to take medication, delivered to patients via an electronic pillbox, may be able to improve adherence to tuberculosis (TB) treatment. The findings, reported this week in PLOS Medicine, are the result of a cluster randomized controlled trial by Shiwen Jiang of the Chinese Centers for Disease Control & Prevention, Katherine Fielding, of the London School of Hygiene & Tropical Medicine, and colleagues.
India: Govt to roll out daily drug treatment for TB (post)
PUNE: The daily drug treatment for tuberculosis (TB) will be rolled out initially in five states, including Maharashtra, Bihar, Kerala, Himachal Pradesh and Sikkim, between January and February next year. The new regimen will replace the existing three times a week treatment and will be implemented across the country in a phased manner thereafter.
India: Medicine for drug-resistant TB patients to benefit 800 in Maharashtra (post)
PUNE, Sep 25, 2015: The new medicine to treat drug-resistant tuberculosis will be rolled out in four Indian cities and will be made available for free.
A proposal for an individualized pharmacogenetic-guided isoniazid dosage regimen for patients with tuberculosis (post)
Background/aim: Isoniazid (INH) is an essential component of first-line anti-tuberculosis (TB) treatment. However, treatment with INH is complicated by polymorphisms in the expression of the enzyme system primarily responsible for its elimination, N-acetyltransferase 2 (NAT2), and its associated hepatotoxicity. The objective of this study was to develop an individualized INH dosing regimen using a pharmacogenetic-driven model and to apply this regimen in a pilot study.
Cigarette smoke is a risk factor for severity and treatment outcome in patients with culture-positive tuberculosis (post)
Objective: Smoking has been associated with tuberculosis (TB); however, the effects of smoking on the effectiveness of TB treatment remain unclear.
Incentives and enablers to improve adherence in tuberculosis (post)
Material incentives and enablers may have some positive short term effects on clinic attendance, particularly for marginal populations such as drug users, recently released prisoners, and the homeless, but there is currently insufficient evidence to know if they can improve long term adherence to TB treatment.
Why HIV/TB coinfected patients are discontinuing treatment at alarming rates (post)
SAN DIEGO, CA—Patients with HIV and tuberculosis (TB) coinfection are discontinuing first-line antitubercular therapy (ATT) at disturbingly high rates because of side effects like skin reactions, gastrointestinal symptoms, and hepatotoxicity, according to study findings reported at IDWeek 2015.
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