Items tagged with Treatment

Bedaquiline: A new hope to MDR-TB patients in the Philippines (post)

The first new drug to treat tuberculosis in more than 40 years, Bedaquiline is helping patients fight multidrug-resistant tuberculosis (MDR-TB) through its donation program – a public-private partnership between United States Agency for International Development (USAID) and Janssen Therapeutics of Johnson & Johnson.

WHO recommendations on shorter MDR-TB treatment (post)

The recent release by WHO of new recommendations aimed at speeding up tuberculosis drug susceptibility testing using a rapid molecular MTBDRsl test and use of shorter multidrug-resistant tuberculosis (MDR-TB) treatment regimens is a long-awaited development. Although the new recommendations are welcomed, there are concerns about whether the shorter MDR-TB treatment regimen is likely to be effective in all geographical settings.

World Health Organization’s TB care advice violated standards, researchers say (post)

Durham, NC - The World Health Organization (WHO) violated sound standards of medical care and human rights by nudging poorer countries to follow less expensive, untested and largely ineffective treatment protocols for tuberculosis patients, a new paper by researchers at Duke, Brandeis and Harvard universities argues. 

India: Daily drug TB treatment to begin in September (post)

The government is set to roll out the daily drug treatment for tuberculosis in Mumbai from September this year, replacing the three-times-a-week treatment schedule. The new treatment protocol for drug-sensitive cases — the regular TB cases that react to first line drugs — will be rolled out in five states including Maharashtra. The new protocol will eventually help bring down relapse rates, and in turn the number of drug-resistant TB cases.

Individual mycobacteria respond differently to antibiotics based on growth and timing (post)

New study identifies differences between subpopulations of mycobacteria with variable antibiotic susceptibilities

Nutritional supplements for people being treated for active TB (post)

Abstract

Background

Tuberculosis and malnutrition are linked in a complex relationship. Tuberculosis may cause undernutrition through increased metabolic demands and decreased intake, and nutritional deficiencies may worsen the disease, or delay recovery by depressing important immune functions. At present, there is no evidence-based nutritional guidance for adults and children being treated for tuberculosis.

Old drugs may offer new hope in resistant TB (post)

New combinations of commercial drugs might be able to effectively treat patients who have built up a resistance to antituberculosis drugs, researchers said.

Shortened regimen for MDR-TB shows good results for children (post)

The use of the shortened 9-month treatment regimen for multidrug-resistant tuberculosis (MDR-TB), known as the ‘Bangladesh regimen’ has shown to be successful in 83% of children and adolescents diagnosed with rifampicin-resistant (RR) TB.

Daily TB treatment better than intermittent (post)

DURBAN, South Africa, July 21 – Patients diagnosed with tuberculosis as well as HIV do better in combating tuberculosis with an intensified daily regimen rather than intermittent therapy that delivers less medicine, researchers reported here.

High-dose rifampicin for TB treatment regimen may improve survival in people with low CD4 cell counts (post)

More aggressive TB treatment using high dose of rifampicin, in addition to ARV treatment, could reduce TB/HIV mortality among co-infected TB/HIV patients with a severe immunocompromised state, according to Corinne Merle of the London School of Hygiene & Tropical Medicine who presented the results of the three-arm RAFA trial last week at the 21st International AIDS Conference (AIDS 2016) in Durban, South Africa.