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Items tagged with Treatment

Drug resistance patterns of drug-resistant TB in Korea (post)

Additional drug resistance patterns among multidrug-resistant TB patients in Korea: implications for regimen design

STREAM community engagement workshop held in Tbilisi, Georgia (post)

The STREAM trial, which is evaluating the effectiveness of shorter treatment regimens for multidrug-resistant tuberculosis (MDR-TB), held a community engagement workshop in Tblisi, Georgia, where the Stage 2 trial is planned to initiate shortly. Stage 2 will study a six-month MDR-TB treatment and a nine-month all oral regimen.

Spero Therapeutics receives grant from National Institutes of Health to explore novel treatment combinations for TB (post)

CAMBRIDGE, Mass., May 4, 2017—Spero Therapeutics, LLC, a biopharmaceutical company founded to develop novel therapies for the treatment of bacterial infections, today announced that it has received a grant from the National Institutes of Health (NIH) to conduct additional preclinical studies of SPR720, the Company’s novel oral bacterial gyrase inhibitor, for the treatment of tuberculosis (TB). The non-dilutive grant of $564,718 is part of the NIH’s Small Business Innovation Research (SBIR) program (Grant Number: 1R44AI131749-01).

Ibrutinib may inhibit macrophage response to TB (post)

Ibrutinib may inhibit the macrophage-mediate response to Mycobacterium tuberculosis (Mtb) among patients with chronic lymphocytic leukemia (CLL), according to an abstract presented at the XVII International Workshop on Chronic Lymphocytic Leukemia (iwCLL).1

Later-generation fluoroquinolones more effective at reducing mortality risk in resistant TB (post)

Later-generation fluoroquinolones significantly reduced the risk for mortality in patients with suspected drug-resistant tuberculosis compared with early-generation drugs of the same family, according to researchers.

Child-friendly TB tablets to be introduced in India (post)

There is good news for children suffering from tuberculosis as the government has started the rollout of the world's first easily-dissolvable and flavoured drug in five states as part of a pilot programme.

ITPCru poster: TB treatment (post)

ITPCru has developed a poster on TB treatment. It is based on the World Health Organization (WHO) guidelines 2010 with taking into account the April 2017 updates.

Directly observed therapy for multidrug-resistant TB decreases mortality (post)

ATS 2017, WASHINGTON, DC ─ Directly observed therapy (DOT) for multidrug-resistant tuberculosis (MDR-TB) was associated with a 77 percent decrease in mortality in the United States, compared to self-administered therapy from 1993 to 2013, according to new research presented at the ATS 2017 International Conference.

Readily available antibiotic could help to curb lung damage from TB (post)

Imperial scientists have found how a common antibiotic could help reduce lung destruction in people with Tuberculosis (TB).

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