Items tagged with Treatment
Linezolid does not increase culture conversion rates in TB (post)
Patients with pulmonary tuberculosis who had linezolid added to their treatment regimen for either 2 or 4 weeks did not have higher culture conversion rates compared with individuals who received standard treatment, according to study results published in the Lancet Infectious Diseases.
Sewri TB hospital starts giving bedaquiline to outpatients (post)
In an attempt to prioritise the comfort of patients suffering from tuberculosis, the civic-run TB hospital in Sewri has started giving bedaquiline in the outpatient department (OPD).
Olainfarm will supply TB drugs to WHO for more than 1 million dollars (post)
Based on a cooperation agreement concluded last year, in the 1st quarter of 2019 JSC Olainfarm will be delivering its PAS-sodium anti-tuberculosis medicine, to the World Health Organisation (WHO) for a total of more than 1 million U.S. dollars. PAS-sodium is a widely known tuberculosis treatment drug that has proven its effectiveness globally, and the WHO is using it to treat tuberculosis in developing countries throughout Asia and Africa.
Diabetic drug improves the efficacy of two TB drugs (post)
A protein essential for the formation of biofilm by TB-causing bacteria (Mycobacterium tuberculosis) has been finally identified by a multi-institutional team from Delhi’s Jamia Hamdard, National Institute of Pathology and Indian Institute of Technology (IIT) Delhi. Biofilm formed by TB bacteria acts as a physical barrier to drugs thereby protecting the microorganisms. The researchers also found two FDA-approved drugs used for treating diabetes and suppressing the immune responses were able to disrupt biofilm formation by the bacteria. When the existing drugs were used along with first-line anti-TB drugs, the dosage required to kill the bacteria was drastically reduced by over 50%. To validate the promising results obtained in the lab, the team has already initiated trials on mice.
Unitaid seeks innovative, long-lasting technologies to help tackle diseases (post)
Geneva – Unitaid is pleased to announce a call for proposals for projects speeding development of long-acting versions of medicines that could potentially revolutionize treatment and prevention of diseases including HIV, tuberculosis and malaria in low- and middle-income countries.
Vitamin D helps treat lethal drug-resistant TB (post)
Vitamin D has been found to speed up the clearance of tuberculosis (TB) bacteria from the lungs of people with multi-drug resistant TB, according to a study of 1,850 patients receiving antibiotic treatment, led by Queen Mary University of London.
Multidrug-resistant TB outcomes with pyrazinamide susceptibility testing (post)
Introducing pyrazinamide molecular susceptibility testing in the treatment of multidrug-resistant tuberculosis improved outcomes without the use of new drugs and shortened the World Health Organization (WHO) 20+ month regimen to 12 months, according to a study published in the European Respiratory Journal.
Immune checkpoint inhibitor therapy and risk of TB exacerbation (post)
Immune checkpoint therapy with programmed cell death-1 (PD-1) inhibitors was linked to activation of latent Mycobacterium tuberculosis (Mtb) infection in 2 patients, according to a case study report published in Science Translational Medicine.
India: Delamanid to be available across the country (post)
Crucial anti-Tuberculosis (TB) drug Delamanid will now be available across India. Until currently, its supply was restricted to seven States.
IMPAACT study on HIV and TB medications taken during pregnancy to begin new phase in 2019 (post)
An ongoing study funded by the National Institutes of Health (NIH) is investigating how women process medications for HIV and tuberculosis (TB) during pregnancy in an effort to inform treatment guidelines for pregnant and postpartum women.
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