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Tuberculosis success

First approval for new tuberculosis drugs paves the way for better combinations of new and old agents.

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Current concepts: Tuberculosis - review article from NEJM

Tuberculosis remains a major cause of death worldwide. The rise and spread of drug resistance and synergistic interaction with the HIV epidemic are posing difficult challenges and threatening global efforts at tuberculosis control.

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Information Note on the use of Xpert MTB/RIF for detection of TB among people living with HIV

The document describes the early evidence on use of the tool – including research findings and modeling results – and provides algorithms for the management of people living with HIV and with presumptive TB.

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New group connects TB and MDR-TB survivors and patients

Together with the website Take That TB, Treatment Action Group has created a listserv to connect TB and MDR-TB survivors and patients interested in conducting advocacy and connecting with others in this community.

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Landmark meeting on post-2015 TB targets held in Geneva

The participants in a workshop convened last week by the World Health Organization (WHO) and the Stop TB Partnership have proposed a set of goals and targets to guide the global fight against TB after 2015.

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Now available online: Video presentations from the Aspiring to Zero satellite symposium

Video presentations from the "Aspiring to Zero TB Deaths, New Infections, and Suffering" symposium held at the 2012 International Union Against TB and Lung Disease World Conference in Kuala Lumpur are now available online! 

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Ahead of WHO meeting, experts clash over tuberculosis targets

Mario Raviglione, director of the WHO's Stop TB Department: “My aim is to reach a consensus right now. If we wait, we may miss the train.”

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Data from historic Phase IIb clinical trial for TB vaccine candidate MVA85A published in The Lancet

Vaccine candidate was generally well tolerated, meeting the study’s primary objective of safety; Vaccine candidate did not provide statistically-significant protection in preventing TB disease in infants previously vaccinated with BCG.

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Cochrane review gives thumbs up to GeneXpert test for detection of MDR-TB

The Cochrane analysis represents the most comprehensive review on the diagnostic accuracy of Xpert and provides evidence that may help countries make decisions about scaling up Xpert for programmatic management of TB and drug-resistant TB.

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Tuberculosis may lurk in bone marrow stem cells of infected patients

By doing so, the bacteria take advantage of the body's own mechanisms of self-renewal.

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