Items tagged with Pediatrics
One in eight children with confirmed TB have drug-resistant TB in Cape Town (post)
One in eight children with confirmed TB have drug-resistant TB in Cape Town, South Africa, according to a surveillance study of childhood TB drug-resistance, presented by Professor Simon Schaaf at the 46th Union World Conference on Lung Health held in Cape Town from 2 to 6 December 2015.
Pharmacokinetics of old and new TB drugs for children (post)
Several presentations at the 46th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease showed pharmacokinetic (PK) data for anti-tuberculosis (TB) drugs in children.
Epidemiology and clinical characteristics of pediatric drug-resistant tuberculosis in Chongqing, China (post)
Abstract
‘Make it stop’: The tender casualties of drug-resistant tuberculosis (post)
In the remote mountains of South Africa, Matsepo rises at 3 am to start the day. She has important work to do, work which is a matter of life or death. Such an early start is necessary for her to wash, get dressed, and prepare tea before waking her feverish, emaciated 5 year-old granddaughter Ntabaleng. She hoists the fairy-light girl onto her back to begin the four-hour walk to the nearest clinic. Ntabaleng’s own mother cannot do this because she is dead, a victim of the same drug-resistant tuberculosis (DR-TB) that is responsible for Matsepo’s daily journey with her precious granddaughter. Ntabaleng must go to the clinic for treatment because she has to receive a daily injection as part of her DR-TB therapy. Although it’s usually difficult for her to even muster the energy to lift her head, she wails as soon as the needle pierces her raw buttocks. “Make it stop grandma,” she sobs, “make it stop.”
UNITAID seeks proposals to scale up better TB treatment for children (post)
GENEVA, 24 March - UNITAID today launched its latest call for funding proposals, focused on scaling up better tuberculosis (TB) treatment for children. Innovative approaches are being sought to ease adoption of new TB drugs and make them more accessible to children in need.
South Africa: New clinical trial may shorten TB treatment for kids (post)
About a million children develop tuberculosis (TB) annually around the world and when they do, they are often forced to try to take tiny handfuls of adult-sized tablets for months. Now, local researchers are looking at ways to make TB treatment for kids shorter and easier.
Interrupted BCG vaccination is a major threat to global child health (post)
At a meeting of the WHO Child TB Subgroup in Cape Town, South Africa, in December, 2015, critical BCG vaccine shortages were reported in many countries. These shortages started in 2013 and continued into 2015. The United Nations Children's Fund (UNICEF) is the main supplier of BCG vaccine to tuberculosis-endemic countries. During this period, two of its four suppliers, the Statens Serum Institute (SSI) in Denmark and the Serum Institute of India experienced technical difficulties that resulted in reduced production capacity. UNICEF reported shortages of 8 million doses in 2013, 23 million doses in 2014, and 17 million doses in 2015.1 Delegates from many countries reported interruption of BCG vaccination programmes due to local stock-outs resulting from unreliable supply.
New fixed-dose paediatric TB formulations now available for procurement through the Global Drug Facility (post)
31 March 2016 – Geneva, Switzerland - The new fixed-dose paediatric formulations are now available for procurement through the Global Drug Facility (GDF): rifampicin 75 mg + isoniazid 50 mg + pyrazinamide 150 mg and rifampicin 75 mg + isoniazid 50. The products dissolve in water, have a fruit flavour, and are simple to administer.
Children with tuberculosis in India suffer on lack of proper fixed-dose combinations (post)
Since 2010, evidence is emerging that doses to treat TB earlier thought to be optimal are less than what a child’s body needs, doctors say
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