Items tagged with Prevention

Lupin partners with global agencies to increase patient access to TB prevention treatment (post)

Makes rifapentine-based treatment available at an affordable price to support TB prevention in low-and middle-income countries

Improving TB prevention programs aimed at HIV patients (post)

The intervention included meeting with experts, texting services to improve and facilitate communication, and data collection and dissemination.

Storytelling to support TB preventive treatment (post)

Three storyboards describe the experiences of people who took TB preventive treatment (TPT): Daud Yamikani of Malawi took a three-month regimen called 3HP after his wife was treated for bone TB, Josephat Asande of Kenya took 3HP when his cousin was staying with him and undergoing treatment for drug-sensitive TB, and Ganesh Acharya of India took TPT for 36 months after a roommate developed TB back in 2009.

Rare genetic disease may protect Ashkenazi Jews against tuberculosis – new study (post)

Tuberculosis, humanity’s greatest infectious killer, is caused by bacteria that usually affect the lungs but can also affect many other organs in the body. In 2021, around 10.6 million people worldwide fell ill with tuberculosis (TB) and 1.6 million people died from the disease.

250,000 patients to benefit from free access to short-course TB prevention treatment across seven countries (post)

Johannesburg, 24 March 2023 – The Unitaid-funded IMPAACT4TB Consortium, led by the Aurum Institute, announced today that it will provide 250,000 patient courses of short course rifapentine-based preventive treatment regimens to seven countries to help prevent tuberculosis (TB). The patient courses will include the three-month 3HP regimen, and the even shorter 1HP, that is only taken for 28 days. This contribution is part of the Consortium’s ongoing efforts to end TB and improve global health outcomes. 

Rifamycin-based TB prevention regimens have lowest adverse event rates (post)

Mono-H regimens are associated with significantly higher rates of serious adverse events (AEs) compared with rifamycin-based regimens among tuberculosis preventive therapy (TPT) options, according to a study in Clinical Infectious Diseases.

TB prevention in England 2021 (post)

The UK Health Security Agency released a report presenting people with TB disease notified to the enhanced surveillance scheme in England and aiming to describe the epidemiology of TB in England up to the end of 2021. It is the sixth in a series of 7 reports that will describe different aspects of TB incidence, treatment and prevention in England.

Failure to implement contact tracing and TB prevention would result in close to 1 million deaths by 2035, according to new study (post)

• People living in close contact with a person with TB disease are at highest risk of infection, and account for a significant percentage of the 10.6 million new TB infections each year. 
• Analysis shows that implementing a combined strategy of identifying household contacts and providing TB preventive treatment is cost-effective and would cut deaths by 35%  among household contacts of all ages and people living with HIV by 2035. 
• Additionally, because TB diagnosis is so low among children under five – just over 3 in 10 children with TB are identified – contact tracing and prevention would have an outsized impact on reducing child death from TB. 
• TB prevention and contact tracing can be delivered cost effectively thanks, in part, to the significant price reductions in short-course therapy achieved in recent years. With further decreases in price and by improving the efficiency and integration of contact tracing into disease responses, the intervention could benefit from greater cost savings and public health benefit. 
• As world leaders prepare for the second United Nations High-Level Meeting on TB this September, up-front multi-stakeholder commitment and financial backing is urgently needed to reap the massive rewards of preventing TB illness and death.

19 July 2023, Johannesburg/Geneva – A new study published today in The Lancet Global Health found that the lives of 850,000 people could be saved by 2035 if short-course tuberculosis (TB) preventive treatment is provided to people living with HIV and contacts of individuals newly diagnosed with TB. 700,000 of those lives saved would be among children aged 15 years and younger. 

Can taking two pills a week slow down TB in South Africa? There’s a new plan in place (post)

• No other disease in South Africa kills as many people as tuberculosis (TB). To change this, the health department has a new plan for curbing TB infections.

• Until now, only people with HIV and children under five could get preventive medicines. But the new guidelines say anyone who has a big chance of getting infected because they are in contact with someone who has TB, can get the pills.

• Preventive treatment can help to stop infections from spreading, but it needs to be part of a bigger strategy if it is to really get us closer to ending TB.

In 2005, when Busisiwe Beko suspected that she was pregnant, she headed to her local clinic for a test. Beko got more than she bargained for: she tested positive for HIV too.

Treating TB contacts ‘saves money’ – study (post)

-- TB preventive treatment could slash deaths rate by 35 per cent
-- Children under five could be biggest beneficiary
-- The preventive treatment will be a cost-effective solution for high-incidence countries