Items tagged with Prevention
PEPFAR launches new effort to fight TB: Goal to detect two million cases and prevent 500,000 deaths (post)
22 September 2023: Today, the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) launched an effort to detect two million active tuberculosis (TB) cases over the next five years and prevent at least 500,000 TB-related deaths among people living with HIV. According to estimates, more than half of the current TB cases among people living with HIV go undiagnosed. PEPFAR and its partners are committed to using new tools and new approaches that dramatically increase TB diagnosis and treatment coverage for people living with HIV.
World Lung Day 2023: Free online course (post)
To mark this year's World Lung Day (September 25), the International Union Against Tuberculosis and Lung Disease (The Union) offered a free online course, Prevent TB: Management of TB infection (Part I & II).
Global prison TB surge exposes WHO guidelines gap (post)
Despite increasing TB rates in prisons across the globe, current World Health Organization (WHO) TB prevention guidelines fail to reach incarcerated populations. Programs should instead prioritize them, argue a group of researchers from a range of global institutions.
WHO announces the release of ScreenTB - a web-based tool to help countries prioritize action for TB screening and prevention (post)
16 October 2023 | Geneva -- WHO’s Global Tuberculosis Programme is pleased to announce the update and release of ScreenTB (screentb.org) - a web-based tool designed to assist countries in prioritizing risk groups for screening, as well as in developing screening and prevention approaches tailored to country contexts.
Assessing uptake of TB preventive treatment in Cameroon and Uganda (post)
The Lancet Global Health journal published two papers on October 30 showing the effectiveness and health economical impact of community-based intervention for household child contact management. Led by the French National Research Institute for Sustainable Development (IRD), the CONTACT study for COmmunity iNtervention for Tuberculosis Active Contact Tracing and preventive therapy, was part of the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF)'s CaP-Tuberculosis (TB) Project.
Spontaneous abortion in women with HIV linked to isoniazid exposure in pregnancy (post)
Exposure to isoniazid prevention therapy during the first trimester of pregnancy is associated with increased risk for fetal demise, according to study results published in Clinical Infectious Diseases.
New child-friendly formulation of rifapentine for short course TB prevention treatment now available as Unitaid and IMPAACT4TB launch an early market access vehicle (post)
More than 2 million children and adolescents lack preventive treatment for TB, which is needed for those living with HIV or exposed to TB at home.
New study: Combo treatment can help solve the TB-HIV co-infection crisis - more than half a million people could benefit (post)
For people starting HIV treatment, combining dolutegravir-containing antiretroviral therapy with 3HP TB preventive treatment is safe and works effectively in tandem.
Comparative analysis of TB preventive therapy efficacies in HIV patients (post)
Latent Tuberculosis Infection (LTBI) is associated with increased immune activation and a heightened risk of cardiovascular diseases. The ACTG A5279 trial, a phase 3 study presented at the Conference on Retroviruses and Opportunistic Infections (CROI), investigated the activation patterns of monocytes in individuals with HIV (PWH). This trial compared the efficacy of 4 weeks of daily rifapentine (RFP) and isoniazid (INH) against 9 months of daily INH for Tuberculosis Preventive Therapy (TPT). At baseline and week 48, PWH with LTBI, compared to those with negative TST/IGRA results, demonstrated changes in monocytes indicative of ongoing activation and tissue migration.
CROI 2024 TB research round up (post)
Treatment Action Group (TAG) released an overview of TB research data reported at the 31st Conference on Retroviruses and Opportunistic Infections (CROI 2024) held on 3-6 March 2024 in Denver, Colorado, USA.
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