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Items tagged with Scientific research

Research charities help marry two major South African HIV/tuberculosis institutes (post)

As the International AIDS Conference kicked off in Durban, South Africa, today, two of the nation’s most prominent biomedical research institutions announced that they will marry and combine resources to attack the raging coepidemic of tuberculosis (TB) and HIV in the region. 

TB vaccine development in the 21st century takes new approaches (post)

DURBAN, South Africa – “Can we control tuberculosis without a vaccine?” asked Willem Hanekom, of the Bill & Melinda Gates Foundation,  Saturday, and answered his own question: “No.”

Researchers identify new mechanism of tuberculosis infection (post)

DALLAS – July 21 2016 – Researchers from UT Southwestern Medical Center have identified a new way that tuberculosis bacteria get into the body, revealing a potential therapeutic angle to explore.

How 3Ps can deliver new drugs for world's biggest killer (post)

Imagine a disease that is the world’s biggest killer, with 1.5 million people dying from it each year. It is a disease that touches every country, but some, such as South Africa, Uzbekistan and India, have been hit particularly hard. This disease has a treatment which, in its simplest form, takes six months to complete. For the complex forms, treatment causes patients to become psychotic, attempt suicide, or permanently lose their hearing due to side effects and offers a 50 percent chance of cure at best; yet in the past 50 years, only two new drugs have been developed to treat a disease that many think is extinct. The disease? Tuberculosis.

STREAM Community Engagement Plan released at AIDS 2016 (post)

The Union, supported by United States Agency for International Development (USAID) through the TREAT TB Cooperative Agreement, and in partnership with The Brazilian Network of Tuberculosis Research (REDE-TB), has released a Community Engagement Plan, designed to support global communities undertaking clinical trials and research in tuberculosis (TB). The plan, launched at the STREAM Joint Community Advisory Board Meeting for community engagement on 15 July, is available from the TREAT TB website.

Toward an effective TB vaccine: Analysis of the immune response to a promising candidate (post)

BCG, the only currently approved TB vaccine, has been around for almost a century and is only partially effective. When given to children, BCG is estimated to prevent 20% of infections and to protect half of the infected individuals from developing active TB, and protection fades over time. Given the complicated TB treatment, the rise of adult TB cases in conjunction with the HIV epidemic, and increasing multidrug resistant TB strains, a new and better vaccine is a global health priority. A study published on July 28th in PLOS Pathogens dissects the immune response in mice to an experimental vaccine and shows why it is highly effective.

HHS forges unprecedented partnership to combat antimicrobial resistance (post)

To address one of the greatest modern threats to public health — antibiotic resistance — the U.S. Department of Health and Human Services (HHS), the Wellcome Trust of London, the AMR Centre of Alderley Park (Cheshire, United Kingdom), and Boston University School of Law will create one of the world’s largest public-private partnerships focused on preclinical discovery and development of new antimicrobial products.

Collaborations Pharma, Inc. and Rutgers announce NIH award to develop treatments for TB (post)

Fuquay-Varina, North Carolina, August 16 – The National Institute of Allergy and Infectious Diseases (NIAID) recently awarded $149,388 to Collaborations Pharma, Inc. (CPI) to initiate a partnership with Rutgers aimed at developing a series of compounds for treating tuberculosis (TB), an infectious disease generally affecting the lungs in humans and caused by the bacterium Mycobacterium tuberculosis (Mtb).

Why Russian TB is the most infectious (post)

Biologists have provided a possible explanation for the epidemiological ‘success’ of tuberculosis strains that are common in Russia and the countries of the former Soviet Union

Researchers find other layers of immunity in TB/HIV co-infections (post)

Tulane University researchers found some monkeys whose immune systems are depleted by the simian strain of HIV have a second line of defense against tuberculosis. The discovery could have significant impacts on future vaccines for TB. The research led by study author Deepak Kaushal, Professor of Microbiology and Immunology at the Tulane National Primate Research Center has been published in the Proceedings of the National Academy of Sciences.

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