Items tagged with Scientific research
Launch of UNITE4TB partnership marks a new era in TB treatment development (post)
The partnership will accelerate the development of new TB drug regimens as part of the Innovative Medicines Initiative (IMI), a public-private European Research & Development Consortium.
LSHTM launches new centre of innovation to tackle antimicrobial resistance and TB (post)
The London School of Hygiene & Tropical Medicine’s (LSHTM) research into tackling antimicrobial resistance and tuberculosis has been boosted through a new partnership with Johnson & Johnson.
Spanish pharmaceutical company Zendal and IAVI partner to advance the TB vaccine candidate MTBVAC into efficacy trials (post)
-- TB kills 1.4 million people a year, an infectious disease toll only recently surpassed by COVID-19.
-- COVID-19 has reversed years of progress in TB response, costing additional lives and adding to the urgency of the global TB problem.
-- MTBVAC is a highly promising vaccine candidate that has the potential to be used as an alternative to BCG vaccination in infants and for prevention of TB disease in adolescents and adults.
Cell-analysis technique could combat TB (post)
A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world.
New insights into TB bacteria mechanism that helps it evade immune system (post)
The fight against tuberculosis (TB) could soon get sharper. Researchers at the Hyderabad-based Centre for DNA Fingerprinting and Diagnostics (CDFD) have got new insight into the molecular mechanism of the TB bacterium that helps it evade the human immune system.
Scientists discover a surprising new way that TB suppresses immunity (post)
Researchers from the University of Maryland found a gene that helps tuberculosis turn off an important immune signaling system in infected human cells.
Hunting for TB's most vulnerable genes (post)
Developing drugs to combat tuberculosis, or TB, can be frustrating business. A gene essential to the bacteria’s lifecycle is discovered, scientists rush to develop drugs that inhibit the target, and then—disappointment. Volleys of compounds hurled at the essential gene target have little impact on microbial growth. The bacteria live on. The scientists return to the drawing board.
NIH awards more than $20 million to international HIV database centers (post)
The National Institutes of Health (NIH) has renewed grants to seven regional centers that compose the International epidemiology Databases to Evaluate AIDS (IeDEA), awarding $20.8 million in first-year funding. The 15-year-old IeDEA program efficiently advances knowledge about HIV by pooling and analyzing de-identified health data from more than two million people with HIV on five continents to answer research questions that individual studies cannot address. The grants are expected to last five years and to total an estimated $100 million.
First 3D view of TB granulomas alters paradigm of their shape and formation (post)
For 70 years, clinicians thought they knew the shape of tuberculosis granulomas in the lungs of patients. Histology — the study of microscopic structures in thin slices of lung tissue in the 1940s and 1950s — showed round features, and researchers intuitively assumed that meant the granulomas were spherical or ovoid.
Weill Cornell advances TB research with support from NIH (post)
Tuberculosis (TB) is a wily old killer, one of the deadliest infectious diseases in history and one of the few that naturally infects only humans. Researchers at Weill Cornell Medicine have been pursuing treatments for tuberculosis caused by Mycobacterium tuberculosis (Mtb) since the 1950s, and the program continues to excel at explaining TB’s mysteries and pushing toward more effective therapies.
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