Items tagged with Scientific research
Ancient DNA confirms marine mammal tuberculosis strains were found in inland people (post)
Tuberculosis is the second most common cause of death worldwide by an infectious pathogen; COVID-19 is the first. However, many aspects of TB's long history remain controversial.
Body's response to different strains of TB could affect transmission (post)
Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.
The new frontier: Spotlight series on mRNA vaccine technology (post)
Messenger ribonucleic acid — known as mRNA — was discovered in the 1960s, but it has reached new heights of popularity among vaccine developers due to its flexibility and adaptability to emerging infectious diseases.
New details behind the body’s response to TB could lead to a more effective vaccine (post)
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CinA protein contributes to drug tolerance in Mycobacterium tuberculosis (post)
Weill Cornell Medicine researchers have identified a protein in Mycobacterium tuberculosis (Mtb) that contributes to drug tolerance, a phenomenon that allows bacteria to survive treatment with drugs that would normally kill them.
Usefulness of monitoring IgG against antigen 85B for prediction of TB development from latency: from an elephant TB analysis (post)
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb); the leading cause of human death due to a single pathogen before the emergence of SARS-CoV-2. In elephants, the infections and deaths with TB have been reported worldwide, and elephant-to-human transmission has also been reported. Therefore, elephant TB is a concern for both conservation of this endangered animal and public health.
Methods combine to decode the biology of tuberculosis (post)
Scientists are fusing sequencing, chemistry and imaging techniques to probe interactions between pathogens and their host cells.
Researchers identify rare genetic markers of drug-resistant TB (post)
Search for rare mutations in bacterial genome could lead to better diagnostics and treatments – reducing morbidity caused by the deadly disease.
A gene in tuberculosis bacteria is found essential for siderophore secretion and virulence (post)
Lei Zhang, Ph.D., and Michael Niederweis, Ph.D., of the University of Alabama at Birmingham have made what they call “a major step” in understanding how Mycobacterium tuberculosis acquires iron from its human host — a process essential for the pathogenesis of this bacterium. Tuberculosis kills more than 1 million people each year, but without iron, M. tuberculosis cannot grow.
Researchers uncover dynamics of adaptive immunity in TB (post)
PITTSBURGH, 17 May 2022 – Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections develops at least twice as slowly. Until recently, the dynamic interplay between bacteria and the host’s immune system remained unclear, hampering the development of effective therapies against the disease, which kills more people worldwide than HIV/AIDS and is second only to COVID-19.
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