Items tagged with Scientific research
Cancer drugs might be able to target TB, study finds (post)
TB lesions in the lungs have high levels of proteins that suppress the immune system. Cancer drugs that target these proteins could be used to fight the bacterial infection.
TB “host-directed therapy” finds novel target (post)
Researchers from the faculty of medicine at the University of Ottawa and their international collaborators say they have shown proof-of-concept for a new therapeutic approach in treating tuberculosis (TB). The disease is caused by a bacterium, Mycobacterium tuberculosis, that infects the lungs and is highly transmissible when infected people cough or sneeze.
TB induces premature cellular aging (post)
Tuberculosis (TB) is a potentially serious infectious disease caused by a type of bacterium called Mycobacterium tuberculosis. The bacteria usually affect the lungs, but also can invade other organs.
Mission end TB: NARI-ICMR moves ahead with phase 3 trials for world’s first TB vaccine (post)
In a breakthrough for eradication of tuberculosis, the Pune-based National AIDS Research Institute (NARI) under the Indian Council of Medical Research (ICMR) is moving forward with phase 3 trials for a vaccine for TB in healthy household contacts or newly diagnosed positive pulmonary TB patients.
Gates MRI looks to Phase 3 TB vaccine trial with epidemiology study (post)
The Bill & Melinda Gates Medical Research Institute (MRI) is conducting a TB epidemiology study: setting the stage for a Phase 3 efficacy trial for its investigational TB vaccine.
TB courses at the McGill Summer Institutes (post)
The McGill Summer Institutes in Global Health announced its 2022 TB summer courses. You can submit your application now! Prices increase after 6 May 2022.
Pathogenic bacteria causing lung diseases hitchhike on red blood cells (post)
Mycobacteria are a group of pathogenic bacteria that cause diseases like leprosy and tuberculosis in humans. Now, a new study by scientists at Hiroshima University finds that mycobacteria are associated with red blood cells at lung infection sites, an interaction that has escaped scientific notice for 140 years since the discovery of the organism causing tuberculosis.
IAVI and Moderna partner to tackle broad global health priorities using mRNA for vaccines and antibodies (post)
NEW YORK, NY and CAMBRIDGE, MA / April 7, 2022 / Moderna, Inc., (NASDAQ:MRNA) a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, and the nonprofit scientific research organization IAVI today announced a new collaboration to employ mRNA technology to meet the challenge of a range of global health threats. These diseases - HIV/AIDS, tuberculosis (TB), antimicrobial-resistant enteric infections, and COVID-19 - are estimated to have caused at least 95 million new infections and more than 4 million deaths in 2020 alone. The collaboration combines the power of Moderna's mRNA platform and IAVI's expertise in discovery and product development to advance vaccines and antibodies designed to be globally accessible, especially in low-income countries where the targeted diseases have high incidence and prevalence.
NIH funds new TB research advancement centers (post)
April 6, 2022: The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced four new grant awards to establish Tuberculosis Research Advancement Centers (TRACs). The centers will support the development of a next generation of tuberculosis (TB) researchers by providing focused mentoring and funding support for new investigators; opportunities for multidisciplinary and collaborative research; and training in laboratory and clinical settings. The total funding in the first year of these five-year grants is approximately $4.3 million.
Researchers identify two distinct tuberculosis subtypes – one has better prognosis than the other (post)
For people who contract tuberculosis (TB), the course of the disease can vary significantly. Most people do not become ill after infection with Mycobacterium tuberculosis, the bacterium that causes the disease. However, people can develop chronic pneumonia and some also have disease in the lymph nodes, bones or the central nervous system. Some TB patients have suppressed and exhausted immune responses, while others have an overacting response that makes the condition worse.
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