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Items tagged with Scientific research

Webinar: Community involvement and engagement in early stage TB research (post)

ERA4TB (European Regimen Accelerator for Tuberculosis) is partnering with fellow IMI-funded TB research consortium, UNITE4TB, on its upcoming webinar on 23 March 2023 from 4-5 pm CET.

Preventing cellular rust hinders TB (post)

Oxygen is, quite literally, the air we breathe (or, more accurately, 21 percent of it). However, just as oxygen in the air can turn a handy garden tool into a useless hunk of rust, certain unstable, oxygen-containing molecules in our bodies can wreak havoc on our cells. According to new IRP research, revving up cellular systems that prevent this kind of damage could significantly improve outcomes for people with tuberculosis.1

How two different types of immune cells help two billion people keep TB in check (post)

New research shows how B cells direct T cells to granuloma tissue in the lungs where they can activate macrophages to neutralize TB infections.

Therapy shows promise to help clear TB (post)

SAN ANTONIO (April 5, 2023) — Texas Biomed scientists have identified a promising way to help fight tuberculosis (TB), a disease that still kills nearly 2 million people annually. The research focuses on a potential host-directed therapy targeting the immune system to bolster the body’s ability to control the infection, a method shown to improve cancer treatments.

Harnessing power of immune system may lessen reliance on antibiotics for infections like TB (post)

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

Discovery may help target TB bacteria ‘dimmer switch’  (post)

A discovery by researchers at the University of Guelph and the Hospital for Sick Children in Toronto may ultimately lead to new therapies for treating tuberculosis (TB).   

One step closer to better drug therapies for TB (post)

AMHERST, Mass., April 18, 2023 – In ongoing research aimed at developing more effective treatments for tuberculosis (TB), University of Massachusetts Amherst microbiologists have identified a long-sought gene that plays a critical role in the growth and survival of the TB pathogen.

TB breakthrough should lead to a new range of TB inhibitors (post)

Tuberculosis (TB) is one of the deadliest infectious diseases worldwide that is spread in the air like the common cold. TB is caused by the bacterium Mycobacterium tuberculosis (Mtb) and was responsible for approximately 1.6 million deaths in 2021. Mtb will usually attack the lungs but can attack any part of the body. Drug resistant TB strains are spreading and present a major concern. New work and a paper by a team of scientists from Manchester, Cambridge and Huddersfield Universities using a structure-guided approach, combined with biophysical characterization obtained a series of compounds with activity against clinically relevant drug-resistant isolates. These will support further development of much-needed additional treatment options against Mtb.

WHO launches the TB research tracker, an online platform to track progress in TB research (post)

5 June 2023 | Geneva-- The World Health Organization (WHO) Global Tuberculosis Programme is launching a new online platform to track progress in the development of new treatment regimens, vaccines as well as operational research projects designed to improve TB prevention, treatment, and care.

NIH grant boosts international TB research consortium (post)

The National Institutes of Health has awarded a five-year, $19.5 million grant to Rutgers University in New Brunswick, New Jersey, for support of Regional Prospective Observational Research in Tuberculosis International, or RePORT International.

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