Items tagged with Scientific research
OVERDUE: Including pregnant participants in TB research - webinar materials now available online (post)
The SMART4TB Consortium hosted a webinar on 20 June 2024 about the consensus process and statement for earlier inclusion of pregnant women and persons in TB research. It featured advocates sharing their experiences with TB and pregnancy, and profiling SMART4TB studies that are responding to the call for inclusion.
Scientists identify 'unconventional' new pathway for TB vaccines (post)
An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.
NIH funds consortium to speed TB treatment development (post)
A new consortium co-led by Weill Cornell Medicine has been awarded a five-year, $31 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis (TB).
T-cell responses as phenotypic shifters in BCG revaccinated adolescents (post)
In the battle against infectious diseases, vaccines are the most powerful allies for building immune responses. In line with this, a recent study indicates that Bacille Calmette-Guérin (BCG) boosters reveal new and existing populations of memory cells, highlighting their protective role against tuberculosis (TB) infection.
New study identifies plasma cfRNA signature as potential biomarker for TB (post)
NEW YORK, Jul 19, 2024 – Circulating cell-free RNA (cfRNA) in blood can potentially be harnessed as a host-response biomarker for tuberculosis, according to a recent study led by Cornell University researchers.
New principle for treating TB (post)
Researchers from Heinrich Heine University Düsseldorf (HHU) and the University of Duisburg-Essen (UDE) have together succeeded in identifying and synthesising a group of molecules that can act against the cause of tuberculosis in a new way. In the scientific journal Cell Chemical Biology, they describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.
New findings on TB could change how we treat inflammatory disorders (post)
Tuberculosis is a confounding scourge. It’s the leading cause of death from infectious disease in the world, and yet it’s estimated that those deaths represent perhaps 5% of infections with Mycobacterium tuberculosis (Mtb). Antibiotics can take credit for saving the lives of some of those with Mtb, but a chasm nevertheless persists between the prevalence of infection and the targeted severity of its impact. A growing body of evidence suggests genetic vulnerabilities to TB account for that gap.
New $5.8 million grant aims to transform the global landscape of TB research (post)
A $5.8 million grant led by Adrie Steyn, Ph.D., of the University of Alabama at Birmingham and the Africa Health Research Institute, or AHRI, in Durban, South Africa, will provide user-requested infected human lung tissue and analytical services to tuberculosis researchers worldwide.
Two new weapons in the battle against bacteria (post with simple image)
Proteases are vital proteins that serve for order within cells. They break apart other proteins, ensuring that these are properly synthesized and decomposed. Proteases are also responsible for the pathogenic effects of many kinds of bacteria. Now chemists at the Technische Universitaet Muenchen (TUM) have discovered two hitherto unknown mechanisms of action that can be used to permanently disarm an important bacterial protease.
Chemist gets U.S. patent for solution to antibiotic resistance problem (post with simple image)
A chemist based at the University of Copenhagen has just taken out a patent for a drug that can make previously multidrug-resistant bacteria once again responsive to antibiotics.
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