Items tagged with Scientific research
Cancer therapies show promise in combating TB (post)
What could cancer teach us about tuberculosis? That’s a question Meenal Datta has been chasing since she was a graduate student.
New enzymatic cocktail can kill TB-causing mycobacteria (post)
Washington, D.C., March 27, 2024 — With resistance to chemical antibiotics on the rise, the world needs entirely new forms of antimicrobials. A new study published in Microbiology Spectrum, a journal of the American Society for Microbiology, shows that an enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis. The research was carried out by scientists at Colorado State University and Endolytix Technologies.
Breakthrough aerosol human infection model gives hope for future TB vaccine development (post)
University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body.
Research uncovers new reasons to target neutrophils for TB therapy (post)
New research from Trinity team at St James's Hospital improves our understanding of how tuberculosis infection causes lung damage and how we might prevent this.
Researchers unveil a hidden trait in Mycobacterium genomes governing stress adaptation (post)
New research led by Qingyun Liu, PhD, assistant professor in the UNC Department of Genetics, has uncovered a genetic feature known as “transcriptional plasticity,” which plays a pivotal role in governing the transcriptional response of Mycobacteria to stressful conditions.
OVERDUE: Including pregnant participants in TB research webinar (post)
The SMART4TB Consortium will host a webinar on 20 June 2024 about the consensus process and statement for earlier inclusion of pregnant women and persons in TB research. Simultaneous translation will be available in French, Spanish, Portuguese and Russian.
Researchers discover a potential vaccine to prevent TB in people of all ages (post)
In a critical global public health development, a candidate vaccine for tuberculosis (TB) has been created using a gene-editing approach.
A new TB vaccine candidate recombinant protein with additional post-translational modifications occurring in Mycobacterium tuberculosis cells (post)
Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide. On the other hand, about one-fourth of the world's population carries Mycobacterium tuberculosis (M. tuberculosis) without showing any symptoms, and most of these carriers do not develop the disease.
Novel 3D hydrogel culture to study TB infection and treatment (post)
Researchers from the Department of Bioengineering (BE), Indian Institute of Science (IISc), have designed a novel 3D hydrogel culture system that mimics the mammalian lung environment. It provides a powerful platform to track and study how tuberculosis bacteria infect lung cells and test the efficacy of therapeutics used to treat TB.
UCF scientist using AI to speed up TB drug discovery (post)
Using Kyle Rohde’s data and artificial intelligence, biotech company Atomwise narrowed its focus from millions of drugs to just 100, accelerating the search for new tuberculosis antibiotics.
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