Items tagged with Scientific research
New TB compound to be developed for Pan-TB regimen (post)
During the 47th Union World Conference on Lung Health, Otsuka Pharmaceutical, the manufacturer of delamanid, announced the development of a second anti-TB compound in its portfolio currently in Phase 1 clinical development. The compound, OPC-167832, is intended to target both drug-susceptible as well as drug-resistant forms of TB, and has a different mechanism of action than all currently approved anti-TB drugs.
IDRI receives $15 million commitment from Eli Lily for TB drug discovery (post)
Seattle, WA | November 3, 2016 : IDRI’s (Infectious Disease Research Institute) drug discovery efforts continue to grow with a recently awarded $7.5 million in additional funding, plus an additional $7.5 million of in-kind services, for a total commitment of $15 million over the next five years from Eli Lilly and Company. The funding and in-kind services, which include Lilly scientists’ time and engagement on projects as well as Lilly research and development resources and capabilities, will extend the work of the Lilly TB Drug Discovery Initiative. This marks the continuation of a long-standing partnership between IDRI and Eli Lilly, which started more than eight years ago with the founding of the Lilly Initiative, a unique public-private partnership that includes IDRI, Lilly and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), with a focus on the discovery of new anti-tuberculosis drugs.
TB-PACTS initiative accepting requests for access (post)
The TB-PACTS initiative represents a collaborative partnership between the Special Programme for Research and Training in Tropical Disease (TDR), the TB Alliance, St. George’s University of London, and Critical Path Institute (C-Path).
ReSeqTB data platform available to public (post)
CPTR is excited to announce the public launch of the ReSeqTB (Relational Sequencing TB Data) platform.
Researchers advance treatment of TB by targeting new enzyme (post)
Researchers at Johns Hopkins report they have laid the foundation to develop novel antibiotics that work against incurable, antibiotic-resistant bacteria like tuberculosis by targeting an enzyme essential to the production and integrity of bacterial cell walls.
Workshop: towards new treatments for TB (post)
The European Medicines Agency (EMA) is organising a workshop on the development of new medicines to treat tuberculosis (TB). The event will take place at EMA’s premises in London on 25 November 2016, from 9:00 to 16:00.
International Journal of Mycobacteriology, September 2016 issue (post)
The International Journal of Mycobacteriology is the journal of the Asian-African Society for Mycobacteriology. It is an open access journal and publishes the most current research related to basic, clinical and epidemiological studies of Mycobacterial infection.
New capsule achieves long-term drug delivery (post)
Researchers at MIT and Brigham and Women’s Hospital have developed a new drug capsule that remains in the stomach for up to two weeks after being swallowed, gradually releasing its drug payload. This type of drug delivery could replace inconvenient regimens that require repeated doses, which would help to overcome one of the major obstacles to treating and potentially eliminating diseases such as malaria.
German government announces support for new TB treatments (post)
The government of Germany has announced its support for the development of new treatments to combat tuberculosis (TB). Germany’s Federal Ministry of Education and Research (BMBF) has committed EUR 10 million over five years to TB Alliance, facilitated by the KfW development bank. This grant is part of a slate of support intended to spur product development to fight neglected diseases.
New compound targets TB bacterium’s defense against the immune system (post)
Developed by chemists at Brown University in conjunction with colleagues at MIT and Cornell, the compound could enable a new drug strategy for treating tuberculosis.
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